My SOP is saying : “if the Minimum MACO observed from the overall matrix is found to be less than LOQof existing available Molecules then LOD Value shall be considered as MACO Value for the results verification”
MACO is in Mg/swab
and LOD/LOQ is in PPM therfore MACO is always less.
For XYZ product:
LOD= 0.1 PPM
LOQ= 0.2 PPM
In this case MACO is more than LOD then MACO is considered as limit.
Till Date I was not converted this MACO value in PPM and compared; now someone suggested me, to convert MACO in PPM and then all MACO values will be less than LOD