You have to look at two things. 1 - does your product withstand the sterilization process (what Boomer was referring to), and 2 - do you get sufficient kill at 115 for 20 minutes.
For 1 - you should run tests (stability, efficacy, etc.) to see if your product is still viable after a steam sterilization cycle
For 2 - run Fo calculations, and see if you are getting the required reduction in bioburden (do you need a 6 log reduction, 5 log reduction, etc.)
For 2 - You will also have to confirm sufficient bioburden reduction by running Biological Indicators in your process validation studies.