For the physico-chemical tests of lab water system validation…
Is it necessary to measure TOC every day in the phase I for purifier water and water for injection?
Instead of using TOC, i can test oxidisable substances?
apart from TOC, pH, conductivity, are there other tests required?
For Microbiological contamination…
in PQ, is it necessary to measure the level of endotoxin at some point (frequency)?
in PQ, Is it necessary to measure the level of specified microorganisms (Escherichia coli, Pseudomonas aeruginosa, Candida albicans…) at same point? If so, which ones should be checked?
Sorry for so many questions.