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F0 and FH

What is the exact difference between Fo and FH values?

Rgds

Chandrashekhar H S

[quote=chandrashekharhs]What is the exact difference between Fo and FH values?

Rgds

Chandrashekhar H S[/quote]

FH provided by an overkill cycle may produce a 12- log reduction of a biological indicator ( 3 log reduction of endotoxin) that exhibits a high resistance to dry heat.

The Fo is a overkill approach provides assurance of sterilization well in excess
of the 10-6 probability of non- sterility (by appling steam)

Regards,