[quote=Austin]Most literature for the PQ of a vial washer states that the following tesating should be perfromed.
- Chemical substances
Can someone explain why endotoxin is performed instead of microbial testing?
We are trying to get away from endotoxin testing as we do not perform it in house and it is expensive!!![/quote]
BET testing is nessacary in PQ of vial washing b/c if the vials wil have previously contaminated with endotoxin, so Hot WFI can get rid or reduce the endotoxin level beore entering the depyrogenator due to this the efficiency and assurity of depyrogenator can be easily get . as far as cost of endotoxin testing, it is not v expensive if you use gel clot method.